Table S4.

AUC and P of ROC curves plotted for TIMP-1 in combination with the genotypic data

With reference to control	Early AMD	CNVM	GA	AMD
TIMP-1
AUC	0.6	0.66	0.72	0.65
P	0.22	0.07	0.04	0.047
TIMP-1 + CFH
AUC	0.53	0.6	0.65	0.76
P	0.7	0.32	0.17	<0.001
TIMP-1 + C3
AUC	0.58	0.53	0.55	0.66
P	0.36	0.77	0.65	0.03
TIMP-1 + CFH + C3
AUC	0.61	0.54	0.58	0.8
P	0.2	0.62	0.43	<0.0001