Table 3.
Association between D-dimer cut-off of 1128 ng/mL and in-hospital mortality using logistic regression.
| Alive | In-hospital death | Univariate |
Multivariable |
|||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |||
| D-dimer > 1128 ng/mL | 459 (44.4) | 86 (71.1) | 3.07 (2.05–4.69) | < 0.001 | 2.08 (1.24–3.54) | 0.006 |
| Age | ||||||
| 50–60 years | 467 (18.6) | 15 (4.2) | 1.90 (0.82–4.75) | 0.15 | 0.96 (0.28–3.19) | 0.94 |
| 60–70 years | 577 (23.0) | 45 (12.5) | 4.60 (2.27–10.63) | < 0.001 | 0.88 (0.28–2.84) | 0.82 |
| 70–80 years | 498 (19.8) | 77 (21.4) | 9.12 (4.63–20.70) | < 0.001 | 3.49 (1.40–9.99) | 0.011 |
| 80–90 years | 361 (14.4) | 135 (37.5) | 22.06 (11.38–49.57) | < 0.001 | 9.74 (3.81–28.59) | < 0.001 |
| 90–110 years | 138 (5.5) | 80 (22.2) | 34.20 (17.12–78.40) | < 0.001 | 14.94 (5.23–47.60) | < 0.001 |
| Cancer | ||||||
| Cancer in remission | 183 (7.3) | 43 (11.9) | 1.87 (1.30–2.64) | 0.001 | 0.80 (0.33–1.76) | 0.56 |
| Active cancer | 146 (5.8) | 43 (11.9) | 2.34 (1.61–3.34) | < 0.001 | 1.84 (0.77–4.11) | 0.15 |
| High blood pressure | 1191 (47.6) | 262 (73.0) | 2.97 (2.33–3.81) | < 0.001 | 0.97 (0.56–1.69) | 0.92 |
| Oral anticoagulation (NOAC or VKA) | 298 (12.0) | 84 (23.5) | 2.26 (1.72–2.96) | < 0.001 | 1.08 (0.53–2.10) | 0.82 |
| Plasma creatinine (μmol/L) | 92.3 ± 86.4 | 139.6 ± 137.5 | 1.00 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.00) | 0.001 |
| Parenchymal opacification in chest CT scan > 50% | 356 (17.8) | 74 (30.0) | 1.98 (1.46–2.64) | < 0.001 | 2.00 (1.16–3.42) | 0.012 |
| Venous thrombosis eventa | 116 (4.6) | 11 (3.0) | 0.65 (0.33–1.17) | 0.18 | 0.72 (0.20–1.98) | 0.56 |
Data are expressed as number (%) or mean ± standard deviation, unless otherwise indicated. CI: confidence interval; CT: computed tomography; NOAC: non-vitamin K antagonist oral anticoagulant; OR: odds ratio; VKA: vitamin K antagonist.
a
Venous thrombosis event included deep vein thrombosis and pulmonary embolism.