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. Author manuscript; available in PMC: 2021 Jun 27.
Published in final edited form as: Curr Opin Genet Dev. 2020 Jun 27;62:30–35. doi: 10.1016/j.gde.2020.05.037

Fig. 1.

Fig. 1.

Two complementary approaches for studying the evolution of quantitative traits. (A) Left panel: Genome-wide scan for positive selection reveals candidate loci showing extreme values for some selection statistic (‘FST’ - Fixation Index; ‘EHH’ - Extended Haplotype Homozygosity; ‘PBS’ - Population Branch Statistic; ‘SDS’ - Singleton Density Score). Right panel: Loci showing strong signals of positive selection are also significantly associated with a quantitative trait (height) in a GWAS in a comparable population. (B) Loci significantly associated with a quantitative trait in a GWAS (left) show a correlated frequency change in the same direction (right), indicating polygenic selection acting on increased height.