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. 2021 Feb 23;12:611323. doi: 10.3389/fmicb.2021.611323

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Copyright © 2021 Du, Huang, Lin, Wang, Yang, Huang, Zheng, Chen, Huang, Wang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of resveratrol on the insulin signaling pathway and fatty acid-related genes in fatty liver mice. (A) Western blotting was used to detect the protein levels of key molecules in the insulin signaling pathway (irs1, p-irs1. mTor, and p-mTor) in the liver among the different groups. (B) Statistical analysis of the protein levels. The relative expressions of genes related to (C) lipogenesis, (D) fatty acid uptake, and (E) fatty acid oxidation were assessed by qRT-PCR. Data are shown as the mean ± SEM, variables were analyzed using Tukey’s test, *p < 0.05; **p < 0.01; ***p < 0.001; and ****p < 0.0001 vs NC group, ^#p < 0.05; ^##p < 0.01; ^###p < 0.001; and ^####p < 0.0001 vs HFD group.