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. 2021 Mar 7;8(1):e000463. doi: 10.1136/lupus-2020-000463

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Increased priming of low-density granulocytes (LDGs) in maternal-derived intervillous blood in women with SLE compared with healthy women. (A) Schematic illustrations made by A-C Lundell that depict decidua basalis with spiral arteries and maternal-derived intervillous blood in relation to fetal villous tissue, which is modified from ref 39. (B) Granulocyte count in intervillous whole blood in women with SLE compared with healthy controls (HCs). (C) Expression of CD62L and CD11b on normal-density granulocytes in women with SLE relative to HC. (D) Percentage of LDGs in women with SLE compared with HC. (E) Expression of CD62L and CD11b on LDG in women with SLE compared with HC. Horizontal bars indicate medians, and each symbol represents one individual. *P≤0.05, Mann-Whitney U test.