Skip to main content
. Author manuscript; available in PMC: 2021 Oct 22.
Published in final edited form as: Adv Funct Mater. 2020 Sep 6;30(43):2004307. doi: 10.1002/adfm.202004307

Figure 5.

Figure 5.

Cardiac functional assessment in the rat acute MI model. A) Representative Masson’s trichrome-stained sections of infarcted rat hearts after 5 weeks treatment with PBS, FR/NPs, MAP gel and FR/drugMAP gel. (Bottom) High-magnification views of the infarcted zones. B) Quantitative analyses of infarcted size (as % of the total LV area). C) Quantitative analyses of infarcted minimum LV wall thickness. D) LVEDV and E) LVESV of infarcted hearts measured by echocardiography at 5 weeks. E) LV ejection fraction (EF) of infarcted hearts at day 2 (baseline) and week 5 after treatment. G) Change in LVEF in comparison to baseline (ΔLVEF). Data are shown as mean ± SD. PBS (n = 9), FR/NPs (n = 6), MAP (n = 9) and FR/drugMAP gel (n = 9). *p < 0.05 and **p < 0.01 indicate significant difference in comparison to the PBS control group. #p < 0.05 and ##p < 0.01 in (F) indicate comparisons of 5 week treated group to the corresponding baseline. NS represents no significant difference.