TABLE 3.
Functional parameters for ex vivo perfused hearts isolated from ad libitum control and high fat diet fed mice
| Control diet Ad libitum | High fat diet Ad libitum | |||
|---|---|---|---|---|
| ZT5 | ZT17 | ZT5 | ZT17 | |
| Cardiac power (CP; mW) | 1.19 ± 0.05 | 1.16 ± 0.06 | 1.15 ± 0.05 | 1.21 ± 0.08 |
| Heart rate (BPM) | 291 ± 15 | 304 ± 10 | 288 ± 9 | 285 ± 9 |
| Developed pressure (mm Hg) | 29.5 ± 3.2 | 31.4 ± 2.3 | 30.3 ± 2.9 | 33.1 ± 1.5 |
| Rate pressure product (BPM × mm Hg) | 8272 ± 656 | 9480 ± 629 | 8653 ± 695 | 9417 ± 497 |
| Oxygen consumption (MVO2; umoles/min/g dry wt) | 7.10 ± 0.68 | 7.56 ± 0.97 | 8.71 ± 1.16 | 7.81 ± 0.69 |
| Cardiac efficiency (CP/MVO2) | 0.18 ± 0.02 | 0.17 ± 0.02 | 0.15 ± 0.02 | 0.16 ± 0.01 |
Data are reported as mean ± SEM for 8‐11 mice per experimental group.