Fig 4. Rabbit catheter-associated sepsis model–CFU in blood, organs, and on catheters.

(A) Bacterial CFU in the blood over time. (B) Bacterial CFU at the time of death or the end of the experiment in the indicated organs. (C) Bacterial CFU in the lumina of implanted catheters. Data are from the second batch of rabbits only (n = 6/group). The dotted line depicts the threshold above which CFU values were considered to reflect biofilm formation in both batches of rabbits. (A-C) Rabbits that developed catheter biofilms are marked by open symbols and light-colored borders.