Table 3. Effect of different doses of berberine on fractional excretion of urate (%) of hyperuricemic rats (n = 6).

Fractional Excretion of Urate (FEUa)%
Groups	Day 0 Mean ± SD	Day 7 Mean ± SD	Paired t-test p-value
Normal control (A)	6.7 ± 4.2	6.8 ± 3.4	0.367
Disease control (B)	6.3 ± 1.7	9.3 ± 4.9	0.188
Standard drug Allopurinol (C)	7.3 ± 1.7	6.4 ± 4.7	0.545
Low dose berberine (D)	9.6 ± 7.7	35.4 ± 13.2	0.007
Medium dose berberine (E)	9.3 ± 3.9	17.4 ± 9.2	0.119
High dose berberine (F)	5.8 ± 3.1	9.4 ± 5.4	0.154
p-value (ANOVA)	0.512	<0.001