Table 5.
Meta-Analysis of Neural Difference Between Youth at High Risk and Controls During Social Task and associations with neural maps.
|
MNI Coordinates |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| x | y | z | Hemisphere | Label | BA | ALE | Neural Map association (r) | |||
| 51 | 22 | −8 | Right | Orbital inferior frontal gyrus | 47 | 0.0090 | Addict | Emp | SC | ToM |
| −11 | −63 | 1 | Left | Lingual Gyrus | 19 | 0.0097 | – | – | – | – |
| 21 | −18 | −37 | Right | Parahippocampal gyrus | 35 | 0.0102 | – | – | – | – |
| 3 | 4 | 11 | Right | Caudate | – | 0.0102 | – | – | – | – |
| 2 | 26 | 53 | Right | Superior Frontal medial gyrus | 8 | 0.0098 | – | – | – | – |
| −21 | −96 | 12 | Left | Middle occipital gyrus | 18 | 0.0094 | – | – | – | – |
| −62 | −26 | 13 | Left | Superior temporal gyrus | 41 | 0.0094 | – | – | – | – |
| 38 | −76 | 19 | Right | Middle occipital gyrus | 19 | 0.0094 | – | – | – | – |
| 10 | 61 | 26 | Right | Superior Frontal medial gyrus | 9 | 0.0094 | 0.01 | 0.08 | 0.39 | 0.43 |
| −9 | −82 | 46 | Left | Superior occipital lobe | 7 | 0.0094 | 0.02 | −0.03 | 0.10 | 0.18 |
| −39 | 24 | 45 | Left | Frontal medial gyrus | 8 | 0.0098 | – | – | – | – |
| 49 | −72 | 34 | Right | Angular gyrus | 39 | 0.0098 | −0.01 | −0.06 | −0.23 | −0.23 |
| −58 | −35 | 47 | Left | Inferior parietal lobule | 40 | 0.0094 | – | – | – | – |
| −58 | 13 | −16 | Left | Superior temporal pole | 38 | 0.0102 | – | – | – | – |
All coordinate anatomical likelihood estimations have an FDR corrected p value of < .001. – = no association.
Addict = addiction map; Emp = Empathy map; SC = Social cognition map; ToM = Theory of mind map.