Fig. 8. Expression of CCL2/MCP-1 and serpin E1/PAI-1 after PLX4032 treatment. (A) TPC1 cells were treated for 72 hours with 10 µM of DMSO (CTL) or PLX4032. (B) 8505C cells were treated for 72 hours with 5 µM of DMSO (CTL) or PLX4032. Density levels of CCL2/MCP-1 and serpin E1/PAI-1 were measured with Bio-Plex 200 system (Bio-Rad, Hercules, CA, USA). CCL2, chemokine (C-C motif) ligand 2; MCP-1, monocyte chemoattractant protein 1; PAI-1, plasminogen activator inhibitor 1; DMSO, dimethyl sulfoxide; CTL, cytotoxic T lymphocyte. *P < 0.05, **P < 0.01 vs. control.
