Figure 1.

Human biventricular electromechanical model properties in healthy and post-MI conditions. (A) Fibre and sheet-normal field. (B) Colour map for local times of activation in the endocardial fast activation layer in milliseconds. (C) ECG electrode placement in 3D space around the biventricular mesh. (D) Electrophysiological transmural heterogeneity, with blue—endocardial cell type, white—mid-myocardial cell type, and red—epicardial cell type. (E) Electrophysiological apex-to-base heterogeneity of the slowly activating delayed rectifier potassium channel current (IKs), with colour map showing conductance for the slow rectifier potassium current. (F) Infarct (red), border zone (white), and remote zone (transparent blue) for an anterior endocardial infarction. (G) Infarct (red), border zone (white), and remote zone (transparent blue) for a transmural left anterior descending artery infarction. (H) Epicardial action potentials and calcium transients for the baseline, ischaemic, acute, and chronic infarct regions. (I) Epicardial action potentials and calcium transient for the baseline, acute, and chronic borderzone regions.