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. 2021 Mar 10;37(7):2305–2312. doi: 10.1007/s00381-021-05104-z

Table 3.

Classification of cases as confirmed, probable, or possible association with SARS-CoV-2 infection

Patient Diagnosis SARS-CoV-2 CNS sample Evidence of other commonly associated causes Provisional case definitions for the association of COVID-19 with neurological disease [8]
1 Guillain-Barré syndrome Negative Negative infectious CSF PCR panel, negative C jejuni PCR Probable
2 Guillain-Barré syndrome Negative Negative infectious CSF PCR panel Possible
3 Guillain-Barré syndrome Negative Negative infectious CSF PCR panel Possible
4 Bilateral optic neuritis, left VI cranial nerve paresis Negative Negative infectious CSF PCR panel Probable
5 Left optic neuritis Negative Negative infectious CSF PCR panel Probable
6 Anti NMDA encephalitis Positive Negative infectious CSF PCR panel Confirmed encephalitis
7 Ischemic stroke Not performed Aortic coarctation Possible
8 Ischemic stroke Not performed Acute myeloid leukemia Possible
9 Myositis Not performed Negative respiratory panel Probable
10 Para infectious ataxia Negative Negative infectious CSF PCR panel Probable