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. 2021 Feb 24;8:628471. doi: 10.3389/fcvm.2021.628471

Table 2.

Plaque phenotype and calcification in culprit lesion segments characteristics by optical coherence tomography.

Parameters Total
(n = 127)
TMAO level p value
High (n = 64) Low (n = 63)
Culprit plaque types
Plaque rupture 62 (48.8) 50 (78.1) 12 (19.0) <0.001
Plaque erosion 57 (44.9) 9 (14.1) 48 (76.2) <0.001
Calcified nodules 8 (6.3) 5 (7.8) 3 (4.8) 0.479
Calcification 94 (74.0) 58 (90.6) 36 (57.1) <0.001
Intimal calcification 82 (64.6) 54 (84.4) 28 (44.4) <0.001
Medial calcification 15 (11.8) 6 (9.4) 9 (14.3) 0.391
Intimal calcified lesions
Eruptive calcified nodules 14 (11.0) 11 (17.2) 3 (4.8) 0.025
Superficial calcific sheet 63 (49.6) 39 (60.9) 24 (38.1) 0.010
Calcified protrusion 5 (3.9) 4 (6.3) 1 (1.6) 0.177
Maximal calcification arc, degree 90.9 (0–193.1) 146.9 (71.3–227.3) 50.0 (0–228.1) <0.001
Maximal calcification thickness, μm 530.0 (0–780) 680.0 (500.0–877.5) 290.0 (0–838.0) <0.001
Calcification length, mm 4.0 (0–11.6) 8.9 (3.5–15.6) 1.6 (0–4.2) <0.001
Smallest depth of calcium, μm 30.0 (10,0–80.0) 20.0 (10.0–60.0) 50.0 (20.0–107.5) 0.013

TMAO, Trimethylamine N-oxide.