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Advantages and disadvantages of CAR-T Cells therapy in Multiple Myeloma.
| Advantages | Disadvantages |
|---|---|
| Novel therapy for refractory/relapsed patients | Potentially can cause life-threatening complications |
| Recognize cells without HLA expression | Relapses after treatment (antigen escape) |
| Eliminates only cells with targeted antigen | Immunogenicity of CARs |
| One-time treatment with long therapy-free intervals providing patients with a high quality of life | High costs of the therapy |
