Table 4.
CTLA-4 and PD-1 haplotype frequencies of the PSS patients and healthy controls.
| Frequency (%) | p | P c | OR | 95% CI | ||
|---|---|---|---|---|---|---|
| PSS 2n = 274 | Control 2n = 278 | |||||
| CTLA-4 rs733618-rs4553808-rs5742909-rs231775-rs3087243 | ||||||
| TACAA | 26.37 | 19.86 | 0.070 | 0.139 | 1.45 | 0.97−2.15 |
| TGTAG | 14.29 | 10.11 | 0.134 | 0.179 | 1.48 | 0.88−2.49 |
| CACGG | 29.30 | 41.16 | 0.004 | 0.015 | 0.60 | 0.42−0.85 |
| TACGG | 30.04 | 28.88 | 0.767 | 0.766 | 1.06 | 0.73−1.53 |
| PD-1 rs10204525-rs2227981-rs2227982-rs41386349-rs36084323 | ||||||
| TAGAC | 20.80 | 19.11 | 0.639 | 0.639 | 1.11 | 0.73−1.68 |
| CAGGC | 7.30 | 4.52 | 0.203 | 0.609 | 1.61 | 0.77−3.35 |
| CGGGC | 20.07 | 17.46 | 0.420 | 0.630 | 1.19 | 0.78−1.83 |
| TGAGC | 0.73 | 3.27 | 0.034 | 0.204 | 0.22 | 0.05−1.02 |
| TAGAT | 0.73 | 1.82 | 0.450 | 0.540 | 0.40 | 0.08−2.07 |
| TGAGT | 50.36 | 53.82 | 0.395 | 0.790 | 0.87 | 0.62−1.21 |
Values in bold indicate significant differences. The p value was calculated using χ2 test or Fisher’s exact test and corrected for multiple testing using the FDR method. PSS, Posner-Schlossman syndrome; Pc: corrected p value; OR, odds ratio; CI, confidence interval.