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. 2021 Feb 24;12:630892. doi: 10.3389/fimmu.2021.630892

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Copyright © 2021 Rindler, Krausgruber, Thaler, Alkon, Bangert, Kurz, Fortelny, Rojahn, Jonak, Griss, Bock and Brunner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Multiplex proteomics identify markers of spontaneously healed AD. Volcano plots of proteins detected by proteomic multiplex assays in suction blister fluid, that are upregulated or downregulated in spontaneously healed atopic dermatitis (n = 4), depicted as log2 fold change (FCH) over active AD lesions (n = 4). Differences between groups were assessed using a linear mixed model (36) and Benjamini-Hochberg correction for multiple testing. Proteins with a –log10 adjusted p > 1 (corresponding to an adjusted p < 0.1) are labeled in red. AD, atopic dermatitis.