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. 2021 Feb 24;12:627547. doi: 10.3389/fpsyg.2021.627547

Table 2.

Explanatory contribution for each risk factor in regression models with increasing number of adjusting factors.

Adjusted by risk factors in other groups NO YES
Adjusted by risk factors in the same group NO YES NO YES
Df R2 (%) CI Rp2 (%) CI Rp2 (%) CI Rp2 (%) CI
Socio-demographic 5 0.60 [0.15, 1.72]* - - 0.04 [-0.11, 0.88] - -
    Age 1 0.27 [−0.02, 0.91] 0.19 [−0.04, 0.77] −0.04 [−0.04, 0.17] −0.04 [−0.04, 0.2]
    Sex 1 0.13 [−0.04, 0.61] 0.06 [−0.04, 0.53] −0.04 [−0.04, 0.17] −0.04 [−0.04, 0.19]
    Education 2 −0.08 [−0.09, 0.28] −0.08 [−0.09, 0.26] 0.16 [−0.07, 0.78] 0.16 [−0.05, 0.77]
    Income 1 0.41 [0.02, 1.2]* 0.30 [−0.02, 0.99] −0.04 [−0.04, 0.23] −0.04 [−0.04, 0.19]
Lifestyles 5 8.09 [5.88, 11.09]* 0.07 [−0.1, 0.96]
    Nutrition 1 0.44 [0.02, 1.19]* 0.04 [−0.04, 0.45] −0.01 [−0.04, 0.31] −0.02 [−0.04, 0.28]
    Cog. activity 1 0.71 [0.16, 1.58]* 0.35 [0, 0.98] 0.04 [−0.04, 0.46] 0.02 [−0.04, 0.42]
    Exercise 2 1.31 [0.52, 2.58]* 0.80 [0.21, 1.87]* 0.00 [−0.08, 0.53] 0.01 [−0.08, 0.56]
    Sleep 1 6.68 [4.46, 9.15]* 6.29 [4.19, 9.04]* 0.05 [−0.04, 0.51] 0.04 [−0.04, 0.53]
Social connectedness 4 13.65 [10.97, 17]* 8.54 [6.39, 11.4]*
    Household structure 3 5.74 [3.89, 7.98]* 6.25 [4.16, 8.7]* 4.79 [3.01, 7.13]* 5.05 [3.29, 7.5]*
    Social Interaction 1 7.89 [5.52, 10.38]* 8.39 [6.06, 10.9]* 3.68 [2.02, 5.4]* 3.94 [2.33, 5.87]*
General health 3 23.80 [19.9, 28.06]* 7.37 [5.07, 10.43]*
    Physical health 1 7.79 [5.62, 10.28]* 0.71 [0.13, 1.82]* 0.75 [0.11, 1.86]* 0.01 [−0.04, 0.45]
    Mental health 1 21.78 [18, 25.87]* 10.55 [7.59, 14.2]* 6.67 [4.4, 9.29]* 4.46 [2.63, 6.82]*
    Cognitive health 1 12.34 [9.29, 15.76]* 1.34 [0.46, 2.71]* 2.78 [1.32, 4.68]* 0.67 [0.06, 1.81]*
Meaning in life 3 24.87 [21.62, 28.45]* 7.04 [4.87, 9.67]*
    Engagement with Life 1 14.30 [11.42, 17.63]* 0.24 [−0.04, 0.85] 3.38 [1.9, 5.19]* 0.07 [−0.04, 0.52]
    Purpose in life 1 17.21 [13.81, 20.58]* 0.94 [0.22, 2.06]* 4.32 [2.53, 6.49]* 0.31 [−0.03, 1.09]
    Sense of coherence 1 22.90 [19.52, 26.52]* 7.93 [5.65, 10.43]* 6.21 [4.15, 8.54]* 2.48 [1.28, 4.22]*

All coefficients of determination are adjusted to take into account the loss of degrees of freedom associated to each risk factor and thus penalize overfit. Whenever other controlling risk factors are included (Models NO-YES, YES-NO, YES-YES), Rp2 corresponds to the coefficient of PARTIAL determination, that is Rp2 is constructed based on the ratio of the variance explained by one risk factor over variance left unexplained by the controlling risk factors. Percentile 95% confidence intervals (CI) were obtained bootstraping, R = 2,000,

(*)

indicating significant associations for which the bottom limit of the 95% CI must be positive. Rows in bold contain coefficients of determination for entire groups of predicting factors, indented rows (not bold) only for a single predicting factor.