Table 1.
Alteration of SE, AL, Schirmer’s test and TBuT in Children within S, SA, OK and OKA group after treatment
| S | SA | P value | OK | OKA | P value | |
|---|---|---|---|---|---|---|
| n = 20 | n = 20 | n = 20 | n = 20 | |||
| Age, years, mean (SD) | 9.7 (1.49) | 9.65 (1.53) | 0.917a | 11.00 (1.17) | 10.9 (1.29) | 0.799a |
| Gender (M:F) | 11:9 | 10:10 | 0.752b | 10:10 | 9:11 | 0.752b |
| SE, D, mean (SD) | ||||||
| Baseline | − 1.93 (0.74) | − 1.98 (0.45) | 0.687a | − 2.75 (0.46) | − 2.85 (0.45) | 0.293a |
| Change at 3 mo | − 2.26 (0.68) | − 2.09 (0.47) | 0.203a | − 2.88 (0.42) | − 2.90 (0.42) | 0.819a |
| Change at 6 mo | − 2.56 (0.65) | − 2.19 (0.45) | < 0.05a | − 2.98 (0.41) | − 2.96 (0.41) | 0.801a |
| Change at 12 mo | − 3.17 (0.59) | − 2.34 (0.47) | < 0.05a | − 3.07 (0.44) | − 3.02 (0.43) | 0.622a |
| Change over 3 mo | − 0.33 (0.14) | − 0.11 (0.07) | < 0.05a | − 0.14 (0.09) | − 0.05 (0.06) | < 0.05a |
| Change over 6 mo | − 0.67 (0.17) | − 0.19 (0.08) | < 0.05a | − 0.24 (0.15) | − 0.10 (0.08) | < 0.05a |
| Change over 12 mo | − 1.30 (0.44) | − 0.34 (0.16) | < 0.05a | − 0.33 (0.16) | − 0.15 (0.08) | < 0.05a |
| AL, mm, mean (SD) | ||||||
| Baseline | 24.28 (0.83) | 24.17 (0.68) | 0.500a | 24.42 (0.48) | 24.56 (0.39) | 0.177a |
| Change at 3 mo | 24.41 (0.82) | 24.21 (0.69) | 0.227a | 24.49 (0.48) | 24.58 (0.39) | 0.385a |
| Change at 6 mo | 24.62 (0.83) | 24.64 (0.39) | < 0.05a | 24.62 (0.51) | 24.64 (0.39) | 0.812a |
| Change at 12 mo | 25.00 (0.87) | 24.46 (0.69) | < 0.05a | 24.72 (0.51) | 24.68 (0.40) | 0.732a |
| Change over 3 mo | 0.13 (0.05) | 0.03 (0.01) | < 0.05a | 0.07 (0.03) | 0.02 (0.02) | < 0.05a |
| Change over 6 mo | 0.31 (0.06) | 0.10 (0.04) | < 0.05a | 0.19 (0.13) | 0.08 (0.05) | < 0.05a |
| Change over 12 mo | 0.72 (0.21) | 0.24 (0.12) | < 0.05a | 0.29 (0.11) | 0.14 (0.08) | < 0.05a |
| Schirmer’s test, s, mean(SD) | ||||||
| Baseline | 18.10 (1.54) | 18.20 (1.57) | 0.775a | 18.15 (1.46) | 18.33 (1.90) | 0.645a |
| Change at 3 mo | 18.02 (1.49) | 18.05 (1.21) | 0.935a | 18.08 (1.30) | 18.18 (1.35) | 0.738a |
| Change at 6 mo | 17.95 (1.56) | 17.98 (1.36) | 0.940a | 18.00 (1.01) | 18.08 (1.20) | 0.764a |
| Change at 12 mo | 17.90 (1.49) | 17.90 (1.73) | 1.000a | 17.90 (0.77) | 17.98 (1.25) | 0.748a |
| Change over 3 mo | − 0.07 (0.65) | − 0.12 (0.96) | 0.787a | − 0.07 (0.85) | − 0.15 (1.02) | 0.731a |
| Change over 6 mo | − 0.15 (1.09) | − 0.22 (1.00) | 0.750a | − 0.15 (1.00) | − 0.25 (1.12) | 0.676a |
| Change over 12 mo | − 0.20 (1.01) | − 0.30 (1.04) | 0.665a | − 0.20 (1.32) | − 0.32 (1.60) | 0.705a |
| TBuT, s, mean(SD) | ||||||
| Baseline | 12.60 (1.53) | 12.65 (1.67) | 0.889a | 12.65 (1.38) | 12.80 (1.52) | 0.646a |
| Change at 3 mo | 12.53 (1.66) | 12.50 (1.51) | 0.944a | 10.73 (1.28) | 10.78 (1.67) | 0.881a |
| Change at 6 mo | 12.48 (1.64) | 12.45 (1.76) | 0.948a | 12.40 (1.59) | 12.48 (1.64) | 0.837a |
| Change at 12 mo | 12.45 (1.63) | 12.40 (1.73) | 0.895a | 12.48 (1.55) | 12.55 (1.66) | 0.835a |
| Change over 3 mo | − 0.07 (0.94) | − 0.15 (0.77) | 0.698a | − 1.92 (0.69) | − 2.22 (0.83) | 0.084a |
| Change over 6 mo | − 0.12 (0.91) | − 0.20 (0.91) | 0.714a | − 0.25 (0.63) | − 0.32 (0.79) | 0.642a |
| Change over 12 mo | − 0.15 (0.66) | − 0.25 (0.84) | 0.556a | − 0.17 (0.67) | − 0.25 (0.87) | 0.668a |
SE spherical equivalent refraction, AL axial length, D dioptre, TBuT tear film break-up time, M:F male:female, SD standard deviation
a Independent samples t test
b Chi-square test