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. 2021 Mar 9;11:5528. doi: 10.1038/s41598-021-84927-x

Figure 6.

Figure 6

Microscopic determination of anti-amyloidogenic activity of CZ particles using TEM (a–f) and AFM (g–l) techniques. Disassembly effect of CZ particles was studied using lysozyme amyloid fibrils incubated alone (control) (a) and in the presence of MCZ (b), and 30 µm synthetic zeolite particles (c). Insulin amyloid fibrils alone (control) (g); incubated in the presence of 3 µm CZ (h) and 20 µm CZ particles (i) at the fibrils to nanoparticle concentration ratio of 1:5 (mg/mg). Inhibitory effect of CZ particles on insulin amyloid fibrils formed alone (d); in the presence of MCZ (e) and 30 µm synthetic zeolite particles (f). Lysozyme amyloid fibrils formed alone (control) (j) and in the presence of 3 µm CZ (k) and 20 µm CZ particles (l) at the fibrils to CZ particle concentration ratio of 1:5 (mg/mg). The data analyses were performed using NanoScope Analysis 1.20 software. White scale bars represent 1 μm.