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. 2021 Mar 9;11:5532. doi: 10.1038/s41598-021-84928-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Linear Discriminant Analysis Effect Size (LEfSe) cladogram of microbial taxa between OB and NW. LEfSe algorithm was performed on Galaxy computational tool v.1.0. (https://huttenhower.sph.harvard.edu/galaxy/). The diameter of each circle is proportional to the abundance of the taxon. Only the differentially abundant taxa at the different taxonomic ranks were indicated. Red bacterial taxa were more abundant in OB; green bacterial taxa were more abundant in NW. NW = normal-weight healthy controls, OB = overweight and obese patients; (a) Bacteroidetes phylum, (b) Firmicutes phylum, (c) Proteobacteria phylum.