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. 2021 Mar 9;11:5493. doi: 10.1038/s41598-021-85009-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The expression of S100A2 in TCE-treated keratinocytes. (A) Microarray analysis of the dysregulated genes in keratinocytes after TCE treatment. (B) GO enrichment analysis of upregulated genes in TCE-treated keratinocytes. (C,D) The list (C) and heat map (D) of top 10 upregulated genes in keratinocytes by TCE. (E) The number of common upregulated genes in telaprevir- and TCE-treated keratinocytes. (F) The list of common upregulated genes in telaprevir- and TCE-treated keratinocytes. Four common upregulated genes within the top 10 lists in both telaprevir and TCE groups are highlighted in red. Results are expressed as the mean ± SD. p-values were obtained by the Student’s t-test: *p < 0.05.