Table 2.
Performance characteristic estimates for each index test.
| Test | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV % (95% CI) | NPV % (95% CI) | YI (95% CI) | Accuracy % (95% CI) |
|---|---|---|---|---|---|---|
| RBT 1:2 | 85.7 (57.2–98.2) | 96.6 (93.1–98.6) | 63.2 (38.4–83.7) | 99.0 (96.4–99.9) | 0.82 (0.81–0.84) | 95.9 (92.3–98.1) |
| RBT 1:8 | 78.6 (49.2–95.3) | 99.0 (96.5–99.9) | 84.6 (54.6–98.1) | 98.5 (95.8–99.7) | 0.78 (0.75–0.80) | 97.7 (94.7–99.3) |
| Amitech | 35.7 (12.8–64.9) | 69.6 (62.8–75.8) | 7.5 (2.5–16.6) | 94.0 (89.0–97.2) | 0.05 (0.02–0.09) | 67.4 (60.8–73.6) |
| Arkray | 64.3 (35.1–87.2) | 65.2 (58.2–71.7) | 11.3 (5.3–20.3) | 96.4 (91.7–98.8) | 0.29 (0.26–0.33) | 65.1 (58.4–71.4) |
| Eurocell | 50.0 (23.0–77.0) | 55.4 (48.3–62.3) | 7.1 (2.9–14.2) | 94.2 (88.4–97.6) | 0.05 (0.02–0.09) | 55.0 (48.2–61.8) |
| Fortress | 28.6 (8.4–58.1) | 75.0 (68.5–80.8) | 7.3 (2.0–17.6) | 93.9 (89.0–97.0) | 0.04 (0.01–0.07) | 72.0 (65.6–77.9) |
| cELISA | 92.9 (66.1–99.8) | 89.2 (84.1–93.1) | 37.1 (21.5–55.1) | 99.5 (97.0–100.0) | 0.82 (0.81–0.83) | 89.4 (84.6–93.2) |
PPV positive predictive value, NPV negative predictive value, YI Youden’s index reported to two decimal places, RBT the Rose Bengal test, cELISA competitive enzyme-linked immunosorbent assay, CI confidence interval.