Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 24;12:642470. doi: 10.3389/fphys.2021.642470

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Lai and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The role of EETs in the pathological changes of cardiac remodeling. (A) Under various stimulus, the heart will go through cardiac remodeling, which is an adaptive process to volume overload or/and pressure overload. During the process, several pathological changes including fibrosis, inflammation, myocardial hypertrophy, apoptosis as well as angiogenesis are involved, which finally caused heart failure. (B) EETs are able to attenuate cardiac remodeling with ameliorated myocardial hypertrophy, reduction in apoptosis and fibrosis, decreased inflammation as well as promotion in angiogenesis.