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. 2021 Feb 24;12:632620. doi: 10.3389/fgene.2021.632620

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Copyright © 2021 Källberg, Vidman and Rydén.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Adjusted Rand index for a gradual increase in number of selected genes. The number of included genes was increased over a 1000 steps from 2 to up to all genes remaining after filtration. Of low expressed genes. The feature selection methods are: dip-test statistic (DIP), bimodality index (BI), modified variance reduction score (mVRS), standard deviation (SD), and the positive control (PVAL). The performance is shown for the KIRP (A), STAD (B), LGG (C), and BRCA (D) data. A running mean over 100 values was applied to get a smoother curve.