Fig. 11.

Threshold shifts after cisplatin 4 × 3 treatment. a The diagram of the 4 × 3 protocol. ABR and DPOAE was tested 3 days prior to the cisplatin treatment for baseline and 6 days after the last injection of cisplatin. b Analyses revealed that a significant increase of ABR threshold shifts was observed across all five frequencies tested in the cisplatin-exposed group (n = 10) compared to the saline group (n = 6). c Analysis of DPOAE threshold shifts also showed significant increases across all five frequencies in the cisplatin-treated group. **p < 0.01 and ***p < 0.001. Data shown are the means ± 1 SEM