Fig. 3.

Changes of ABR wave 1 latencies after cisplatin 4 × 1 treatment. ABR wave 1 latencies at 10 kHz (a), 20 kHz (b), 28 kHz (c), and 40 kHz (d) were measured before cisplatin injection (solid red lines) or saline injection (solid black lines) and post-cisplatin (dashed red lines or dashed black lines). Sample sizes were n = 6 for the saline group and n = 10 for the cisplatin group. Points where the cisplatin post-exposure latencies were higher than at 10 kHz and 40 kHz at same SPL (a, d) or sensation level (e, h). *p < 0.05, **p < 0.01, and ***p < 0.001. Data shown are the means ± 1 SEM