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Threshold shifts after cisplatin 4 × 2 treatment. a Diagram of the 4 × 2 protocol. Animals were sacrificed 10 days after the last cisplatin injection. b, c Six days after the 4 × 2 treatment, analyses showed that both ABR and DPOAE threshold shifts were increased significantly in high-frequency regions in the cisplatin group (n = 10), but not the saline group (n = 6), measured 6 days after the last injection. **p < 0.01 and ***p < 0.001. Data shown are the means ± 1 SEM
