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. 2021 Feb 24;12:620433. doi: 10.3389/fphar.2021.620433

FIGURE 1.

FIGURE 1

Effects of long term-UUO and treatment of eplerenone (EPL) on renal histology, fibrosis, and function of the contralateral kidneys. Kidney sections from all groups were stained with HE for morphology changing (A), Masson's Trichrome (Masson) for fibrosis (B), and Sirius red for collagen deposition (C). Images are representative for n = 12 rats each group. (D) BUN and Scr in serum were evaluated for renal function. Renal scores and quantification data are presented as mean ± SEM, n = 6. *p < 0.05 vs. the sham, #p < 0.05 vs. the UUO.