Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 24;12:620433. doi: 10.3389/fphar.2021.620433

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Xiong, Chang, Hao, Zhang, Yang, Wang, Liu, Wang, Mu and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of aldosterone and MR blocker spironolactone (Spir) on the expression of α-SMA in macrophages. (A) mRNA levels expression of α-SMA in cell line macrophages, RAW264.7 cells, treated with or without additional aldosterone and Spir. Data are mean ± SEM. n = 3 independent tests. *p < 0.05 vs. control; #p < 0.05 vs. Aldosterone. (B) Two-color flow cytometry analysis show protein level expression of α-SMA in macrophage cell line (RAW264.7, upper panel) and mouse bone marrow derived macrophages (lower panel). Numbers in red color indicating the percentage of MMT cells with α-SMA⁺, F4/80⁺. Data are representative for n = 5–7 independent tests.