Table 1.
Participant information: descriptive, clinical variables, head movement during scanning and distribution of scan modalities, for each group sample and tasks: resting state (RS), stop signal paradigm (STOP), reward processing (REWARD), working memory (WM).
| N used in final analyses | Age min – max | Age mean (std) | % female** | Siteb | Inattentiona (std) | Hyperactivitya (std) | IQ** (std) | Root mean square head movement (std) | |
|---|---|---|---|---|---|---|---|---|---|
| Healthy control participants | |||||||||
| RS | 84 | 10.8 – 23.5 | 16.7 (3) | 50% | 65% | 0.4 (1.1) | 0.3 (0.8) | 107.2 (13.8) | 0.14 (0.17) |
| STOP | 46 | 10.8 – 23.4 | 16.7 (3.1) | 58.7% | 50% | 0.3 (1.0) | 0.2 (0.6) | 106.1 (14.1) | 0.10 (0.06) |
| REWARD | 46 | 12.7 – 23.5 | 16.6 (2.9) | 50% | 55% | 0.6 (1.5) | 0.3 (0.9) | 108.1 (12.8) | 0.16 (0.11) |
| WM | 66 | 10.8 – 23.5 | 16.5 (3.1) | 50% | 80% | 0.3 (1.0) | 0.3 (0.8) | 105.8 (13.4) | 0.18 (0.16) |
| Unaffected Siblings | |||||||||
| RS | 93 | 7.7 – 28.1 | 16.9 (4) | 57% | 45% | 0.7 (1.4) | 0.6 (1.1) | 101.6 (14.9) | 0.16 (0.21) |
| STOP | 55 | 7.7 – 27.3 | 17.1 (4.1) | 54.5% | 36% | 0.7 (1.7) | 0.7 (1.3) | 102.6 (16.3) | 0.10 (0.10) |
| REWARD | 57 | 9.1 – 28.1 | 17.2 (3.7) | 57.9% | 49% | 0.6 (1.4) | 0.7 (1.2) | 100.1 (15.2) | 0.11 (0.07) |
| WM | 44 | 7.7 – 28.1 | 16.2 (4.1) | 56.8% | 54% | 0.3 (1.0) | 0.3 (0.7) | 102.6 (13.7) | 0.15 (0.21) |
| ADHD participants | |||||||||
| RS | 89 | 8.5 – 24.5 | 17.4 (3.1) | 31.5% | 38% | 7.3 (1.9)* | 5.8 (2.3)* | 94.4 (14.5) | 0.24 (0.38) |
| STOP | 49 | 11.1 – 24.5 | 17.7 (2.7) | 22.4% | 37% | 7.3 (1.5)* | 5.3 (2.3)* | 95.8 (14.7) | 0.09 (0.05) |
| REWARD | 57 | 10.2 – 24.5 | 17.7 (3.1) | 35.1% | 32% | 7.0 (1.5)* | 6.1 (2.0)* | 97.0 (14.9) | 0.17 (0.20) |
| WM | 51 | 10.2 – 24.2 | 17.2 (3.23) | 35.3% | 47% | 7.5 (1.3)* | 5.8 (2.3)* | 94.6 (14.3) | 0.24 (0.21) |
Replication of analysis for differences in sample (scanner/site, gender, IQ) is available in Figs. S1 and S2.
For participant exclusion, see Table S6. **For more detail on IQ and gender representation and testing of differences, see Fig. S7.
aCombined symptoms from KSADS and Conners.
bRatio of Amsterdam/Nijmegen scan localisation.