Fig. 3. Network analysis of the E. faecalis accessory genomes, as defined by Panaroo²⁶, depicts no prominent host-specific clustering.

Nodes indicate separate isolates, connected when shared ≥95% of their accessory genome, and colour-coded according to their isolation sources as indicated in the legend: hospitalised patient (red), wild bird (dark blue), non-hospitalised person (light blue), old human isolates (black), environment (green), farm animal (pink) and others (grey). Components of less than five isolates were filtered out, and the resulting network was visualised using Cytoscape⁷⁸. Source data are provided as a Source Data file.