Table 3.
Differential expression of immune checkpoint molecules in FP.
| CheMyd_1.0 Gene Symbol | Human Ortholog Gene Symbol | Immune checkpoint molecule | log2 FoldChange | lfcSE | padj |
|---|---|---|---|---|---|
| LOC102933512 | PDCD1LG2 | PD-L2 | 3.27 | 0.45 | 0.0001 |
| BTLA | BTLA | BTLA | 3.59 | 0.57 | 0.0009 |
| LAG3 | LAG3 | LAG-3 | 6.41 | 1.42 | 0.01 |
| LOC102947343 | CTLA4 | CTLA-4 | 4.39 | 1.11 | 0.09 |
| LOC114022564 | CD276 | B7-H3 | 1.99 | 0.36 | 0.19 |
| LOC114021416 | CD276 | B7-H3 | 3.74 | 1.00 | 0.20 |
| CD274 | CD274 | PD-L1 | 1.92 | 0.38 | 0.35 |
| LOC102941709 | HAVCR2 | TIM-3 | 1.81 | 0.35 | 0.46 |
| LOC114022559 | CD276 | B7-H3 | 3.14 | 1.10 | 0.83 |
| LOC114018541 | CD274 | PD-L1 | 0.49 | 0.71 | 1 |
| CD276 | CD276 | B7-H3 | 0.15 | 0.33 | 1 |
| LOC102929593 | CD276 | B7-H3 | 0.48 | 0.28 | 1 |
| LOC114018946 | CTLA4 | CTLA-4 | 2.05 | 0.87 | 1 |
| HHLA2 | HHLA2 | B7-H7 | 0.09 | 0.50 | 1 |
| PDCD1 | PDCD1 | PD-1 | 2.05 | 0.58 | 1 |
| LOC114018671 | TMIGD2 | CD28H | 1.16 | 0.43 | 1 |
| VSIR | VSIR | VISTA | 1.37 | 0.32 | 1 |
| VTCN1 | VTCN1 | B7-H4 | −0.75 | 0.61 | 1 |