Table 3.
Conservancy analysis of the CHIKV epitopes in the MAYV structural polyprotein.
| CD8+ T cell Epitope (CTL) | |||
|---|---|---|---|
| Epitope | Conservancy_Hit CHIKV | Conservancy_Hit MAYV | Combined Score |
| KVTGYACLV | 100.00% (1/1) | 100.00% (1/1) | 0.869 |
| ALSVVTWNK | 100.00% (1/1) | 100.00% (1/1) | 1.2483 |
| KYDLECAQI | 100.00% (1/1) | 100.00% (1/1) | 0.9517 |
| KPGDSGRPI | 100.00% (1/1) | 100.00% (1/1) | 1.6136 |
| KPGRRERMC | 100.00% (1/1) | 100.00% (1/1) | 0.8161 |
| RRERMCMKI | 100.00% (1/1) | 100.00% (1/1) | 1.2916 |
| GRRERMCMK | 100.00% (1/1) | 100.00% (1/1) | 0.9834 |
| TGTMGHFIL | 100.00% (1/1) | 100.00% (1/1) | 0.9569 |
| FEVKHEGKV |
100.00% (1/1) |
100.00% (1/1) |
1.0928 |
| CD4+ T cell Epitope (HTL) | |||
| Epitope |
Conservancy_Hit CHIKV |
Conservancy_Hit MAYV |
SMM IC50 Value |
| ALSVVTWNKDIVTKI | 100.00% (1/1) | 100.00% (1/1) | 162 |
| LSVVTWNKDIVTKIT | 100.00% (1/1) | 100.00% (1/1) | 162 |
| VVTWNKDIVTKITPE | 100.00% (1/1) | 100.00% (1/1) | 165 |
| SVVTWNKDIVTKITP | 100.00% (1/1) | 100.00% (1/1) | 166 |
| VTWNKDIVTKITPEG | 100.00% (1/1) | 100.00% (1/1) | 170 |
| MCMKIENDCIFEVKH | 100.00% (1/1) | 100.00% (1/1) | 187 |
| RTLLSQQSGNVKITV | 100.00% (1/1) | 100.00% (1/1) | 205 |
| DRTLLSQQSGNVKIT | 100.00% (1/1) | 100.00% (1/1) | 209 |
| PDRTLLSQQSGNVKI | 100.00% (1/1) | 100.00% (1/1) | 211 |
| TLLSQQSGNVKITVN |
100.00% (1/1) |
100.00% (1/1) |
240 |
| B cell Epitope (BCL) | |||
| Epitope |
Conservancy_Hit CHIKV |
Conservancy_Hit MAYV |
Score |
| GGRFTIPTGAGKPGDSGRPI | 100.00% (1/1) | 100.00% (1/1) | 1 |
| LVGDKVMKPAHVKGTIDNAD | 100.00% (1/1) | 100.00% (1/1) | 0.752 |