Table 4. Multivariate logistic regression analysis for breast response.
Clinicopathological factors | Estimate | SE | Wald | P value | OR (95% CI) |
---|---|---|---|---|---|
cT | |||||
T1 | Ref. | ||||
T2 | ‒1.1841 | 0.3244 | 13.3258 | 0.0003*** | 0.306 (0.162–0.578) |
T3 | ‒1.7059 | 0.4165 | 16.772 | <0.0001*** | 0.182 (0.080–0.411) |
cN | |||||
N0 | Ref. | ||||
N1 | ‒1.077 | 0.238 | 20.4691 | <0.0001*** | 0.341 (0.214–0.543) |
N2–3 | ‒1.0305 | 0.3829 | 7.2446 | 0.0071** | 0.357 (0.168–0.756) |
Histological grade | |||||
I | Ref. | ||||
II | ‒1.6924 | 0.8243 | 0.8243 | 0.0400* | 0.184 (0.037–0.926) |
III | ‒1.5579 | 0.966 | 2.6009 | 0.1068 | 0.211 (0.032–1.399) |
Unknown | 1.862 | 0.771 | 5.8328 | 0.0157* | 6.437 (1.420–29.170) |
PR status | |||||
Negative | Ref. | ||||
Positive | -0.9769 | 0.2555 | 14.6251 | 0.0001*** | 0.376 (0.228–0.621) |
Ki67 expression | |||||
Low | Ref. | ||||
High | 0.6456 | 0.3017 | 4.5789 | 0.0324* | 1.907 (1.056–3.445) |
HER2 | |||||
Negative | Ref. | ||||
Positive | 0.0127 | 0.2449 | 0.0027 | 0.9585 | 1.013 (0.627–1.637) |
Unknown | 0.9531 | 0.3043 | 9.8075 | 0.0017** | 2.594 (1.428–4.710) |
*, P<0.05; **, P<0.01; ***, P<0.001. SE, standard error; OR, odds ratio; CI, confidence interval; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.