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. 2021 Feb;10(2):656–669. doi: 10.21037/gs-20-686

Table 7. Association rules analysis between breast pCR and axillary response.

Rule ID Antecedent (LHS) Consequent (RHS) Support Confidence Lift
1 cT = T2, cN = N0, Breast pCR Axillary pCR 0.05 0.95 2.48
2 cT = T2, cN = N0, Histology = Invasive Ductal, Breast pCR Axillary pCR 0.05 0.95 2.48
3 cN = N0, PR = Negative, Breast pCR Axillary pCR 0.06 0.95 2.47
4 cN = N0, Histology = Invasive Ductal, PR = Negative, Breast pCR Axillary pCR 0.06 0.95 2.47
5 cN = N0, PR = Negative, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.06 0.95 2.46
6 cN = N0, Breast pCR Axillary pCR 0.07 0.95 2.46
7 cN = N0, PR = Negative, Surgery = Mastectomy, Breast pCR Axillary pCR 0.06 0.95 2.46
8 cN = N0, Histology = Invasive Ductal, PR = Negative, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.06 0.95 2.46
9 cN = N0, Histology = Invasive Ductal, Breast pCR Axillary pCR 0.07 0.95 2.46
10 cN = N0, Histology = Invasive Ductal, PR = Negative, Surgery = Mastectomy, Breast pCR Axillary pCR 0.06 0.95 2.46
11 cN = N0, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.07 0.95 2.46
12 cN = N0, PR = Negative, CT Course ≤5, Breast pCR Axillary pCR 0.06 0.95 2.46
13 cN = N0, PR = Negative, Surgery = Mastectomy, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.06 0.95 2.46
14 cN = N0, Surgery = Mastectomy, Breast pCR Axillary pCR 0.07 0.95 2.46
15 cN = N0, Histology = Invasive Ductal, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.07 0.95 2.46
16 cN = N0, Histology = Invasive Ductal, Surgery = Mastectomy, Breast pCR Axillary pCR 0.07 0.94 2.46
17 cN = N0, Histology = Invasive Ductal, PR = Negative, CT Course ≤5, Breast pCR Axillary pCR 0.06 0.94 2.46
18 cN = N0, Histology = Invasive Ductal, PR = Negative, Surgery = Mastectomy, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.06 0.94 2.46
19 cN = N0, Surgery = Mastectomy, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.07 0.94 2.45
20 cN = N0, PR = Negative, CT Course ≤5, Regimen = Chemotherapy, Breast pCR Axillary pCR 0.05 0.94 2.45

, top 20 rules sorted by confidence and lift. support, the frequency of one rule occurrence in the total dataset; confidence, the probability of the RHS in cases of fulfilling the LHS, thus reflecting the reliability of the inference drawn by that rule (LHS → RHS); lift, the realistic probability of co-occurrence of LHS and RHS in a rule divided by the expected probability of LHS and RHS co-occurring, assuming that both of them are independent, as a measure of significance. LHS, left-hand-side; RHS, right-hand-side; pCR, pathologic complete response; ER, estrogen receptor; PR, progesterone receptor; CT, chemotherapy. Association rules mining was conducted under the condition that the LHS for breast response was set as ‘Breast pCR’ while the RHS for axillary response was with no restriction.