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Putative PEG conformation regimes with respect to the polymer concentration in (A), the bilayer, and (B) the curvature of the bilayer of the lipid-based nano-carriers. The curvature is high and mushroom of PEG on the surface of the nanoparticles will form when the value of the D > 2R F. The brush-like structure with relative low curvature of PEG molecule will appear when the value of the D ＜ R F.
