Reconstitution of MIA-3 restores hCC-MSC-Exo-induced proliferation, migration, and invasion of HT-29 and HCT-116 cells in vitro. (A) CCK-8, (B) wound-healing, and (C) crystal violet staining Transwell invasion assays were used to examine the effects of MIA3 overexpression on proliferation, migration, and invasion in HT-29 and HCT-116 cells with or without hCC-MSC-Exo treatment. *P<0.05 vs. control group; #P<0.05 vs. hCC-MSC-Exo group.