Table 3. Univariate logistic regression analysis and diagnostic performance of selected parameters associated with biliary atresia in the derivation cohort.
| Variable | Standardized β | OR (95% CI) | P value | AUC (95% CI) | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) |
|---|---|---|---|---|---|---|
| Weight at admission | 0.458 | 2.37 (1.42, 3.98) | 0.0032 | 0.61 (0.55, 0.68) | 93.9 (86.3, 98.0) | 27.59 (20.5, 35.6) |
| Abnormal gallbladder | 0.559 | 6.46 (2.7, 15.46) | <0.0001 | 0.70 (0.64, 0.76) | 57.32 (45.9, 68.2) | 83.33 (65.6, 80.6) |
| Triangular cord sign | 0.605 | 12.75 (3.93, 41.37) | <0.0001 | 0.68 (0.61, 0.74) | 39.02 (28.4, 50.4) | 96.50 (92.0, 98.9) |
| Clay-colored stools | 0.402 | 4.29 (1.81, 10.18) | 0.0017 | 0.74 (0.68, 0.80) | 87.8 (78.7, 94.0) | 55.56 (47.1, 63.8) |
| γ-glutamyl transpeptidase at admission | 0.818 | 1.003 (1.002, 1.005) | <0.0001 | 0.82 (0.77, 0.87) | 76.83 (66.2, 85.4) | 75.17 (67.3, 82.0) |
| Δ Total bilirubin | 0.863 | 1.016 (1.008, 1.024) | <0.0001 | 0.77 (0.70, 0.82) | 81.71 (71.6, 89.4) | 62.76 (54.3, 70.6) |
| Albumin at admission | −0.306 | 0.92 (0.83, 0.99) | 0.0255 | 0.51 (0.44, 0.58) | 31.71 (21.9, 42.9) | 76.55 (68.8, 83.2) |
AUC, area under the curve; CI, confidence interval.