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. 2021 Feb;10(2):225–235. doi: 10.21037/tp-20-170

Table 4. Effectiveness of risk stratification based on the screen model and clay stool of biliary atresia in derivation and validation cohort.

Biliary atresia screen method Cutoffs Derivation cohort (n=227) Validation cohort (n=234)
No. of cholestatic infants classified into each risk group, N (%) No. of biliary atresia classified into each risk group, N (%) Detection rate of biliary atresia in each risk group (%) Detection rate of biliary atresia in the total population (%) No. of cholestatic infants classified into each risk group, N (%) No. of cases classified into each risk group, N (%) Detection rate of esophageal high-grade lesions in each risk group (%) Detection rate of biliary atresia in the total population (%)
High risk group in the screen model ≥0.49998 77 (33.9) 66 (80.5) 85.7 82/227 (36.1) 85 (36.3) 72 (80.0) 84.7 90/234 (38.5)
Intermediate risk group in the screen model <0.49998, >0.05317 83 (36.6) 16 (19.5) 19.3 85 (36.3) 18 (20.0) 21.2
Low risk group in the screen model ≤0.05317 67 (29.5) 0 0 64 (27.3) 0 0
Clay-colored stools in the total population Presence 71 (31.3) 42 (51.2) 59.2 62 (26.5) 35 (38.9) 56.5