Table 2. Detailed information of the 4 patients who maintained PR or SD for at least 6 months with pembrolizumab.
Sex | Age | Subtype | ECOG score | LDH | Treatment time | PD-L1 | Treatment group | Therapeutic response | Time to progression |
---|---|---|---|---|---|---|---|---|---|
M | 52 | ASPS | 2 | 0 | Second-line | NA | Pembrolizumab alone | PR | Not reached |
F | 45 | UPS | 0 | 0 | Second-line | NA | Combined AD | PR | Not reached |
M | 79 | ESCS | 2 | 1 | Second-line | Positive | Combined lenvatinib | PR | 13 months |
M | 47 | AS | 1 | 0 | First-line | Positive | Combined AD | CR | Not reached |
ECOG, Eastern Cooperative Oncology Group; PR, partial response; CR, complete response; SD, stable disease; PD-L1, programmed cell death-ligand 1; LDH, lactate dehydrogenase; ASPS, alveolar soft part sarcoma; UPS, undifferentiated pleomorphic sarcoma; ESCS, exoskeletal chondrosarcoma; AS, angiosarcoma; NA, not available; AD, anthracycline and dacarbazine.