Table 2. Final prediction model of posthepatectomy liver failure in the derivation cohort.
| Variable | Parameter estimate | Adjusted OR (95% CI) | P value |
|---|---|---|---|
| Gender | |||
| Male | – | Ref | |
| Female | −1.0763 | 0.341 (0.239–0.486) | <0.0001 |
| Age | 0.0291 | 1.030 (1.017–1.043) | <0.0001 |
| Preoperative serum platelet count (×109/L) | −0.0020 | 0.998 (0.996–1.000) | 0.0277 |
| Preoperative serum creatinine level (umol/L) | −0.0143 | 0.986 (0.974–0.997) | 0.0153 |
| Preoperative serum GGT level (U/L) | |||
| <60 | – | Ref | |
| 60–180 | 0.0934 | 1.098 (0.799–1.508) | 0.5640 |
| ≥180 | 0.5418 | 1.719 (1.176–2.512) | 0.0051 |
| Preoperative serum fibrinogen concentration (g/L) | −0.2237 | 0.800 (0.685–0.934) | 0.0047 |
| TT (s) | 0.1074 | 1.113 (1.014–1.223) | 0.0251 |
| HBe-Ag | |||
| Negative | – | Ref | |
| Positive | 0.6348 | 1.887 (1.184–3.007) | 0.0076 |
| Liver segment count excised | |||
| 3 | – | Ref | |
| 3+ | 0.2658 | 1.304 (0.814–2.090) | 0.2690 |
| 4 | 0.8440 | 2.326 (1.696–3.189) | <0.0001 |
| 4+ | 1.3119 | 3.713 (2.099–6.568) | <0.0001 |
| ≥5 | 1.4121 | 4.105 (1.768–9.531) | 0.0010 |
The criterion for variables in Table 1 included in multivariable logistic regression is: P value of univariate analysis ≤0.20. The backward stepwise selection method was used in multivariable logistic regression (αsls=0.05). OR, odds ratio; GGT, gamma-glutamyltransferase; TT, thrombin time; HBe-Ag, hepatitis B e antigen.