Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb;9(4):349. doi: 10.21037/atm-21-367

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

Brain regions showing different fALFF values between the MDD and HC groups at different age-onset (adolescents, young, middle-aged, old). (A) Regions showing significant inter-group differences in the adolescent group; (B) regions showing significant inter-group differences in the young group; (C) the increased and decreased fALFF for patients with middle-age onset relative to HC; (D) fALFF differences between MDD patients and HC in the old group. The warm color represents the higher fALFF of MDD compared to HC. The cold color represents the lower fALFF of MDD compared to HC. fALFF, fractional amplitude of low frequency ﬂuctuations; MDD, major depressive disorder; HC, healthy controls.