Table 2. Distribution of brain regions associated with the one-sample t-test results for the MDD and HC groups and the spatially overlapping area between the two groups.

Anatomical	Hemisphere	BA	Cluster voxels	MNI (x, y, z)	t value
MDD
Medial superior frontal gyrus
Precuneus	30.1	2.7	22.2	24.8	28.2
Posterior cingulate cortex	1,003.6	3.9	996.4	997.0	1,001.3
Posterior cingulate cortex	56.2	15.1	22.9	30.6	46.4
Middle cingulate cortex	1.7	0.4	1.1	1.1	1.4
Middle cingulate cortex	116.8	35.6	37.0	56.2	88.0
Anterior cingulate cortex
Supramarginal gyrus	26.0	3.5	12.3	19.0	23.9
Supramarginal gyrus	1,006.3	4.4	994.3	999.5	1,003.4
HC
Medial superior frontal gyrus	R	10	46	3, 54, 9	17.08
Precuneus	L	23	187	−3, −54, 21	44.94
Precuneus	R	0	175	3, −63, 36	18.08
Cuneus	L	0	55	−3, −72, 30	19.79
Posterior cingulate cortex	L	23	40	−3, −50, 27	26.71
Middle cingulate cortex	L	23	35	−3, −37, 36	16.55
Angular gyrus	L	7	87	−39, −63, 39	32.51
Angular gyrus	R	39	66	48, −63, 30	24.27
Supramarginal gyrus	R	40	37	60, −41, 33	15.50
Inferior parietal gyrus	L	40	48	−42, −52, 46	14.85
The spatially overlapping regions
Anterior cingulate cortex	L	24	30	−3, 27, 30	20.45
Medial superior frontal gyrus	L	32	48	−3, 41, 33	9.98
Precuneus	L	23	160	−3, −54, 24	54.80
Precuneus	R	0	111	3, −60, 30	14.15
Posterior cingulate cortex	L	23	60	−3, −50, 27	42.59
Middle cingulate cortex	L	23	57	−3, −39, 36	13.84
Middle cingulate cortex	R		38	3, −41, 36	16.55
Angular gyrus	L	22	83	−54, −54, 24	16.91
Supramarginal gyrus	R	40	46	57, −48, 30	19.92

BA, Brodmann area; MDD, major depressive disorder; HC, healthy controls.