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. 2021 Feb;9(4):349. doi: 10.21037/atm-21-367

Table 3. Statistical parameters of age-related GLM.

fALFF T-statistic P R2/R Fitting curve
MDD
   Left MCC 5.06 0.0254 0.0212 y=−0.10331 gender + 1.1452
HC
   Right precuneus 6.00 0.0029 0.0492 y= 0.00045 age2 − 0.0389 age + 2.2795
   Left PCC 4.94 0.0079 0.0409 y=0.00042 age2 − 0.0339 age + 1.9475
   Left MCC 7.31 0.0008 0.0592 y=0.00041 age2 − 0.0326 age + 1.5395
   Right MCC 7.63 0.0006 0.0617 y=0.00042 age2 − 0.0361 age + 1.7386
   Left AG 4.41 0.0131 0.0367 y=0.00029 age2 − 0.0227 age + 1.2888
   Right SMG 5.63 0.0010 0.0682 y=0.00030 age2 − 0.0246 age + 0.1287 gender + 1.2514

Note: R2 in R2/R represents the curve fitting degree of the age-related quadratic fitting curve, expressed in italic values; R represents the correlation between fALFF and gender. GLM, general linear model; MDD, major depressive disorder; HC, healthy controls; MCC, middle cingulate cortex; PCC, posterior cingulate cortex; AG, angular gyrus; SMG, supramarginal gyrus.