. 2021 Jan 18;204(1):78–95. doi: 10.1111/cei.13561

Table 1.

Patient variables stratified according to the sPD‐L1 level

Variable		sPD‐L1 ≤ 11·8 pg/ml	sPD‐L1 > 11·8 pg/ml	P‐value
Disease extent	HD	9	8	0·0049
Disease extent	CC	2	19
% T cells	≤ 64·8	1	12	0·0238
% T cells	> 64·8	10	11
% Total CD56^dim NK cells	≤ 15·5	9	10	0·0045
% Total CD56^dim NK cells	> 15·5	2	23
% Total CD56^bright NK cells	≤ 0·77	6	17	0·4344
% Total CD56^bright NK cells	> 0·77	5	6
% PD‐1⁺CD3⁺ T cells	≤ 63	9	13	0·2525
% PD‐1⁺CD3⁺ T cells	> 63	2	10
% PD‐1⁺TIGIT⁺CD3⁺ T cells	≤ 21·9	9	10	0·064
% PD‐1⁺TIGIT⁺CD3⁺ T cells	>21·9	2	13
% PD‐1^hi+CD3⁺ T cells	≤ 20·3	4	7	> 0·9999
% PD‐1^hi+CD3⁺ T cells	> 20·3	7	16
% Total PD‐1⁺ CD56^dim CD16^bright NK cells	≤ 13·4	7	10	0·4646
% Total PD‐1⁺ CD56^dim CD16^bright NK cells	> 13·4	4	13
% Total PD‐1⁺CD56^neg CD16^bright NK cells	≤ 16	7	9	0·2743
% Total PD‐1⁺CD56^neg CD16^bright NK cells	> 16	4	14	0·2743

TIGIT = T cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine‐based inhibition motif (ITIM) domains; Tim3 = T cell immunoglobulin and mucin‐domain containing‐3; PD‐1 = programmed cell death 1; sPL‐L1 = soluble programmed cell death ligand 1; NK = natural killer; HD = healthy donor; CC = cervical cancer.

Bold indicates significant resluts with P ≤ 0·05.