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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Biomaterials. 2020 Sep 16;265:120387. doi: 10.1016/j.biomaterials.2020.120387

Figure 5.

Figure 5.

RNASeq validation on the expression changes of genes related to chondrogenesis for IPFSCs cultured on dECM deposited by SV40LT transduced cells. GSEA for expressed genes ranked by the fold change of expression (C5C/CC for the leftmost panel, C5C/C15C for the middle panel and S15C/S5C for the rightmost panel) against the MSigDB gene set annotated for Gene Ontology chondrocyte development (A). GSEA for expressed genes ranked by the fold change of expression (S15C/C15C) against the MSigDB gene sets related to chondrogenesis including protein hydroxylation, glycolytic through fructose 6 phosphate (F6P), extracellular matrix component, peptidyl proline modification, protein folding chaperone and collagen trimer (B).