TABLE 1.
HIV-1 diversity over time
| Diversity measureb | Median (interquartile range) for time perioda: |
Pd | |||
|---|---|---|---|---|---|
| 1990–1999 | 2000–2004 | 2005–2009 | 2010–2015 | ||
| No. of subtypes/CRFs/URFc | 6 (1–25) | 6.5 (1–36) | 8 (1–39) | 7 (1–39) | 0.0341 |
| No. of CRFsc | 1 (0–16) | 2 (0–26) | 3 (0–29) | 3 (0–29) | <0.0001 |
| Recombinant proportion | 0.050 (0–0.145) | 0.084 (0.017–0.235) | 0.134 (0.016–0.437) | 0.164 (0.032–0.528) | <0.0001 |
| CRF proportion | 0.017 (0–0.075) | 0.047 (0–0.148) | 0.072 (0.007–0.365) | 0.092 (0.005–0.420) | 0.0003 |
| Other CRF proportion | 0 (0–0.008) | 0.005 (0–0.033) | 0.009 (0–0.041) | 0.010 (0–0.072) | <0.0001 |
| URF proportion | 0.004 (0–0.027) | 0.011 (0–0.067) | 0.018 (0–0.063) | 0.028 (0.003–0.095) | 0.0028 |
| Shannon diversity index | 0.727 (0.251–1.122) | 0.753 (0.259–1.236) | 0.833 (0.262–1.353) | 0.943 (0.361–1.393) | 0.2881 |
a
Medians and interquartile ranges for country level values of different diversity measures across four time periods are shown (from 1990 to 2015), except as noted in footnote c.
b
CRF, circulating recombinant form; URF, unique recombinant form; Other CRF, CRFs other than CRF01_AE and CRF02_AG.
c
For these values, the medians and ranges are indicated.
d
P values were determined using the Kruskal-Wallis test.