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. 2021 Feb 17;93(8):3717–3725. doi: 10.1021/acs.analchem.0c03185

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© 2021 American Chemical Society

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Comparison of the mRNA transcripts detected in parental cells and their progeny EVs. (a) Unsupervised hierarchical clustering indicating normalized enrichment of the mRNA levels detected in the PC3-Epi cells and PC3-EMT cells in comparison to their progeny EVs. (b, c) Venn diagrams representing common and unique detected mRNAs in PC3-Epi cells versus PC3-EMT cells and PC3-Epi EVs versus PC3-EMT EVs, respectively. (d) Venn diagrams representing common and unique parts of mRNA transcripts, which are exclusively detected in PC3-EMT cells (not in PC3-Epi cells), versus mRNA transcripts, which are exclusively detected in PC3-EMT EVs (not in PC3-Epi EVs). (e, f) Venn diagrams representing common and unique detected mRNAs in PC3-Epi cells versus PC3-Epi EVs and PC3-EMT cells versus PC3-EMT EVs, respectively.