Table 1.
Demographic and clinical characteristics of patients prescribed any UC medication [Objective A-1]
Year | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 |
---|---|---|---|---|---|---|---|---|---|---|---|
Patients prescribed UC medicationsa, n | 121 | 146 | 168 | 278 | 501 | 945 | 1594 | 2346 | 3977 | 4534 | 6215 |
Sex, male, n [%] | 76 [62.8] | 98 [67.1] | 111 [66.1] | 187 [67.3] | 309 [61.7] | 604 [63.9] | 1034 [64.9] | 1547 [65.9] | 2597 [65.3] | 2927 [64.6] | 3973 [63.9] |
Age, years, median [IQR] | 40.0 [33.0, 47.0] | 39.0 [33.0, 46.5] | 39.0 [33.0, 45.0] | 39.0 [32.3, 46.0] | 40.0 [32.0, 47.0] | 41.0 [33.0, 48.0] | 42.0 [34.0, 49.0] | 42.0 [35.0, 50.0] | 43.0 [35.0, 51.0] | 43.0 [35.0, 51.0] | 44.0 [36.0, 52.0] |
Medical institution visited during the follow up period, n [%] | |||||||||||
University hospital | 19 [15.7] | 18 [12.3] | 19 [11.3] | 44 [15.8] | 85 [17.0] | 143 [15.1] | 219 [13.7] | 346 [14.7] | 543 [13.7] | 603 [13.3] | 952 [15.3] |
National/public hospital | 31 [25.6] | 31 [21.2] | 30 [17.9] | 52 [18.7] | 79 [15.8] | 128 [13.5] | 228 [14.3] | 308 [13.1] | 529 [13.3] | 602 [13.3] | 807 [13.0] |
Clinic [<20 beds] | 33 [27.3] | 47 [32.2] | 60 [35.7] | 98 [35.3] | 186 [37.1] | 337 [35.7] | 555 [34.8] | 846 [36.1] | 1460 [36.7] | 1729 [38.1] | 2358 [37.9] |
Other hospitalb | 43 [35.5] | 61 [41.8] | 70 [41.7] | 103 [37.1] | 178 [35.5] | 377 [39.9] | 687 [43.1] | 978 [41.7] | 1670 [42.0] | 1861 [41.0] | 2445 [39.3] |
Unknown | 4 [3.3] | 4 [2.7] | 4 [2.4] | 1 [0.4] | 0 | 0 | 0 | 3 [0.1] | 1 [0.0] | 2 [0.0] | 2 [0.0] |
Abbreviations: 5-ASA, 5-aminosalicylic acid; CS, corticosteroid; IQR, interquartile range; PSL, prednisolone; UC, ulcerative colitis.
aThe following UC medications were included in the analysis: 5-ASA (salazosulfapyridine [oral, suppository], mesalazine [oral, suppository, enema]), CS (PSL [oral], PSL sodium succinate [injection]), thiopurine (azathioprine [oral], mercaptopurine hydrate [oral]), biologics [infliximab, adalimumab, golimumab, vedolizumab] and others (tofacitinib citrate [oral], tacrolimus hydrate [oral]).
bHospital with ≥20 beds other than a university hospital or national/public hospital.